Publications

Xin Tang, Julie Kim, Li Zhou, Eric Wengert, Lei Zhang, Zheng Wu, Cassiano Carromeu, Alysson R. Muotri, Fred H. Gage, and Gong Chen (2016). KCC2 rescues functional deficits of human neurons derived from Rett syndrome patients. Proc Natl Acad Sci USA. 2016 Jan 5.

Jacy Wagnon, Niccolo Mancacci, Bryan Barker, Eric Wengert, Manoj Patel, and Miriam Meisler (2018). Partial loss-of-function of sodium channel SCN8A in familial isolated myoclonus. Human Mutation. 2018 May 18.

Erin Baker, Christopher Thompson, Nicole Hawkins, Jacy Wagnon, Eric Wengert, Manoj Patel, Alfred George, Miriam Meisler, Jennifer Kearney (2018). The novel sodium channel modulator GS458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy. Epilepsia. 2018 May 21.

Rosie Bunton-Stasyshyn*, Jacy Wagnon*, Eric Wengert, Bryan Barker, Alexa Faulkner, Pravin Wagley, Kritika Bhatia, Julie Jones, Marissa Maniaci, Jack Parent, Howard Goodkin, Manoj Patel, and Miriam Meisler (2019). Prominent role of forebrain excitatory neurons in SCN8A encephalopathy. Brain. 2019 Jan 2.

Eric Wengert, Anusha Saga, Payal Panchal, Bryan Barker, Ronald Gaykema, and Manoj Patel (2019). Prax330 reduces persistent and resurgent sodium channel currents and neuronal excitability in a mouse model of SCN8A encephalopathy. Neuropharmacology. 2019 July 3.

Eric Wengert*, Cathrine Tronhjem*, Jacy Wagnon, Katrine Johannesen, Hayley Petit, Ilona Krey, Anusha Saga, Payal Panchal, Samantha Strohm, Jorn Lange, Sussanne Kamphausen, Guido Robboli, Johannes Lemke, Elena Gardella, Manoj Patel, Miriam Meisler, and Rikke Moller (2019). Biallelic inherited SCN8A variants, a rare cause of developmental and epileptic encephalopathy. Epilepsia. 2019 October 18.

Eric Wengert and Manoj Patel (2020). The role of the persistent sodium current in epilepsy. Epilepsy Currents. 2020 November 25.

Ian Wenker, Frida Teran, Eric Wengert, Pravin Wagley, Payal Panchal, Elizabeth Blizzard, Priyanka Saraf, Jacy Wagnon, Howard Goodkin, Miriam Meisler, George Richerson, and Manoj Patel (2021). Postictal death is associated with tonic phase apnea in a mouse model of SUDEP. Annals of Neurology. 2021 February 18.

Eric Wengert (2021). Mentor as you’d want to be mentored. Science. 2021 February 19.

Eric Wengert, Ian Wenker, Elizabeth Wagner, Pravin Wagley, Ronald Gaykema, Jung-Bum Shin, and Manoj Patel (2021). Adrenergic mechanisms of audiogenic seizure-induced death in a mouse model of SCN8A encephalopathy. Frontiers in Neuroscience. 2021 March 4.

Eric Wengert and Manoj Patel (2021). One size doesn’t fit all: Variant-specific effects in SCN8A epileptic encephalopathy. Epilepsy Currents. 2021 March 16.

Eric Wengert (2021). Learning to unplug. Science. 2021 August 20.

Eric Wengert, Raquel Miralles, Kyle Wedgwood, Samantha Strohm, Payal Panchal, Abrar Majidi Idrissi, Ian Wenker, Pravin Wagley, Jeremy Thompson, Ronald Gaykema, and Manoj Patel (2021). Somatostatin-positive interneurons contribute to seizures in SCN8A epileptic encephalopathy. The Journal of Neuroscience. 2021 September 20.

Jeremy Thompson, Raquel Miralles, Eric Wengert, Pravin Wagley, Wenxi Yu, Ian Wenker, and Manoj Patel (2021). Astrocyte Reactivity in a Mouse Model of SCN8A Epileptic Encephalopathy. Epilepsia Open. 2021 November 26.

Eric Wengert, Pravin Wagley, Samantha Strohm, Nuha Reza, Ian Wenker, Ronald Gaykema, and Manoj Patel (2021). Targeted Augmentation of Nuclear Gene Output of Scn1a Rescues Parvalbumin Interneuron Excitability and Reduces Seizures in a Mouse Model of Dravet Syndrome. Brain Research. 2021 November 26.

Keisuke Kaneko, Christopher B. Currin, Kevin M. Goff, Eric R. Wengert, Ala Somarowthu, Tim P. Vogels, and Ethan M. Goldberg (2021). Developmentally Regulated Impairment of Parvalbumin Interneuron Synaptic Transmission in a Mouse Model of Dravet Syndrome. Cell Reports. 2022 March 29.

Funded Fellowship Grants

NIH Predoctoral Individual National Research Service Award
Depolarization block of inhibitory neurons impacts neuronal function in epileptic encephalopathy

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